9/18
Watch
15 min?
W01
Saturday
Sandbox
optional
Khan Academy, Energy and enzymes → Activation energy
Saturday sandbox
· after OpenStax Biology 2e, ch. 3 "Biological Macromolecules"
Khan Academy, Energy and enzymes → Activation energy (article) — One article + the practice set. Moved out of core on 2026-09-29
In: LABLOOP-W01 Notebook
10/18
Watch
15 min?
W01
Saturday
Sandbox
optional
Crash Course Biology #3 · "Biological Molecules — You Are What You Eat"
Saturday sandbox
· after Khan Academy, Energy and enzymes → Activation energy
Crash Course Biology #3 · "Biological Molecules — You Are What You Eat" — youtube.com/watch?v=H8WJ2KENlK0. Moved out of core on 2026-09-29
In: LABLOOP-W01 Notebook
11/18
Watch
15 min?
W01
Saturday
Sandbox
optional
Khan Academy (MCAT) · "Enzymes and activation energy"
Saturday sandbox
· after Crash Course Biology #3 · "Biological Molecules — You Are What You Eat"
Khan Academy (MCAT) · "Enzymes and activation energy" — khanacademy.org/…/v/enzymes-and-activation-energy. Moved out of core on 2026-09-29
In: LABLOOP-W01 Notebook
12/18
Watch
15 min?
W01
Saturday
Sandbox
optional
LearnChemE · "Washout Derivation in CSTR Bioreactor (Bio)"
Saturday sandbox
· after Khan Academy (MCAT) · "Enzymes and activation energy"
LearnChemE · "Washout Derivation in CSTR Bioreactor (Bio)" — watch?v=L_bzv0bbU4M. The engineer's version of what happens when the feed stops — which is exactly Friday's injected fault
In: LABLOOP-W01 Notebook
13/18
Watch
15 min?
W01
Saturday
Sandbox
optional
MIT OCW 18.06 Linear Algebra
Saturday sandbox
· after LearnChemE · "Washout Derivation in CSTR Bioreactor (Bio)"
MIT OCW 18.06 Linear Algebra (Gilbert Strang), lectures 1-3 — ocw.mit.edu/courses/18-06-linear-algebra-spring-2010. Only if 3Blue1Brown leaves you wanting proofs
In: LABLOOP-W01 Notebook
14/18
Watch
15 min?
W01
Saturday
Sandbox
optional
NPTEL Bioreactors
Saturday sandbox
· after MIT OCW 18.06 Linear Algebra
NPTEL Bioreactors (Suraishkumar, IIT Madras), lecture 1 — nptel.ac.in/courses/102106053. A preview of week 09. (verify) course numbering
In: LABLOOP-W01 Notebook
7/15
Watch
15 min?
W02
Saturday
Sandbox
optional
3Blue1Brown · Neural Networks
Saturday sandbox
· after OpenStax Biology 2e, ch. 7 "Cellular Respiration"
3Blue1Brown · Neural Networks, ch. 1-2 — Topic page: 3blue1brown.com/topics/neural-networks. Moved out of core on 2026-09-29
In: LABLOOP-W02 Notebook
8/15
Watch
15 min?
W02
Saturday
Sandbox
optional
Steve Brunton
Saturday sandbox
· after 3Blue1Brown · Neural Networks
Steve Brunton (@Eigensteve) · SVD series, first 3 videos — playlist PLMrJAkhIeNNSVjnsviglFoY2nXildDCcv, overview video watch?v=gXbThCXjZFM. PCA's engine explained by an engineer; you will want this again in weeks 12-17
In: LABLOOP-W02 Notebook
10/15
Watch
15 min?
W02
Saturday
Sandbox
optional
Ninja Nerd · glycolysis and Krebs cycle lectures
Saturday sandbox
· after Deisenroth, Faisal & Ong, Mathematics for Machine Learning, ch. 10 "Dimensionality Reduction wit…
Ninja Nerd · glycolysis and Krebs cycle lectures (long, whiteboard) — channel search by title, only if respiration is still abstract. (verify) no fixed video ID recorded
In: LABLOOP-W02 Notebook
8/20
Watch
15 min?
W03
Saturday
Sandbox
optional
ISLP
Saturday sandbox
ISLP ch. 2 and 3.1-3.3 — statlearning.com (free PDF) + the matching Stanford Statistical Learning with Python videos. Moved out of core on 2026-09-29
In: LABLOOP-W03 Notebook
11/20
Watch
15 min?
W03
Saturday
Sandbox
optional
Crash Course Statistics
Saturday sandbox
· after Kourti & MacGregor (1995), "Process analysis, monitoring and diagnosis, using multivariate proje…
Crash Course Statistics (YouTube), episodes on the normal distribution and control charts' ancestor, the z-score
In: LABLOOP-W03 Notebook
13/20
Watch
15 min?
W03
Saturday
Sandbox
optional
Stanford Online · Statistical Learning with Python
Saturday sandbox
· after James, Witten, Hastie, Tibshirani & Taylor, An Introduction to Statistical Learning with Applica…
Stanford Online · Statistical Learning with Python (Hastie, Tibshirani et al.) — Playlist: youtube.com/playlist?list=PLoROMvodv4rPP6braWoRt5UCXYZ71GZIQ · course page: online.stanford.edu/courses/sohs-ystatslearningp-statistical-learning-python. Moved out of core on 2026-09-29
In: LABLOOP-W03 Notebook
9/17
Watch
15 min?
W04
Saturday
Sandbox
optional
StatQuest · "Bootstrapping Main Ideas!!!"
Saturday sandbox
· after Sandve G. et al., "Ten Simple Rules for Reproducible Computational Research", PLOS Comp. Biol. 9…
StatQuest · "Bootstrapping Main Ideas!!!" — Channel: youtube.com/@statquest — search the exact title. (verify): no stable video ID confirmed on 2026-09-15. Moved out of core on 2026-09-29
In: LABLOOP-W04 Notebook
7/12
Watch
15 min
W06
Saturday
Sandbox
optional
3Blue1Brown "Bayes theorem, the geometry of changing beliefs"
Saturday sandbox
· after McHugh (2012), "Interrater reliability: the kappa statistic"
3Blue1Brown "Bayes theorem, the geometry of changing beliefs" (YouTube, 15 min)
In: LABLOOP-W06 Notebook
8/12
Watch
15 min?
W07
Saturday
Sandbox
optional
Ninja Nerd "Enzyme kinetics" lecture
Saturday sandbox
· after Karpathy, "Deep Dive into LLMs like ChatGPT"
Ninja Nerd "Enzyme kinetics" lecture (YouTube) for Michaelis-Menten in depth
In: LABLOOP-W07 Notebook
6/15
Watch
15 min?
W08
Saturday
Sandbox
optional
3Blue1Brown Neural Networks ch. 3-4 ("Backpropagation, intuitively"
Saturday sandbox
· after Kadlec, Gabrys & Strandt (2009), "Data-driven soft sensors in the process industry"
3Blue1Brown Neural Networks ch. 3-4 ("Backpropagation, intuitively" and "Backpropagation calculus")
In: LABLOOP-W08 Notebook
8/15
Watch
15 min?
W08
Saturday
Sandbox
optional
Simon Peyton Jones, "How to write a great research paper"
Saturday sandbox
· after Stanford CS231n notes "Backpropagation, intuitions"
Simon Peyton Jones, "How to write a great research paper" (YouTube) — watch now, not in week 18, because the report is a mini-paper
In: LABLOOP-W08 Notebook
3/10
Watch
15 min?
W09
Saturday
Sandbox
optional
MIT OCW 10.37 Chemical and Biological Reaction Engineering
Saturday sandbox
MIT OCW 10.37 Chemical and Biological Reaction Engineering (Spring 2007), lecture notes on bioreactors — ocw.mit.edu/courses/10-37-chemical-and-biological-reaction-engineering-spring-2007
In: LABLOOP-W09 Notebook
5/10
Watch
15 min?
W09
Saturday
Sandbox
optional
LearnChemE "mass balance" screencasts
Saturday sandbox
· after Coursera Industrial Biotechnology
LearnChemE "mass balance" screencasts (YouTube)
In: LABLOOP-W09 Notebook
6/10
Watch
60 min
W09
Saturday
Sandbox
optional
Karpathy "Intro to Large Language Models"
Saturday sandbox
· after LearnChemE "mass balance" screencasts
Karpathy "Intro to Large Language Models" (YouTube, 1 h) for a bird's-eye view
In: LABLOOP-W09 Notebook
4/11
Watch
15 min?
W10
Saturday
Sandbox
optional
ritvikmath "Gaussian Processes"
Saturday sandbox
ritvikmath "Gaussian Processes" (YouTube, whiteboard intuition)
In: LABLOOP-W10 Notebook
5/11
Watch
15 min?
W10
Saturday
Sandbox
optional
StatQuest "Confidence Intervals, Clearly Explained" and "The Standard Error"
Saturday sandbox
· after ritvikmath "Gaussian Processes"
In: LABLOOP-W10 Notebook
8/12
Watch
15 min?
W11
Saturday
Sandbox
optional
Brunton "Bayesian optimization" lecture
Saturday sandbox
· after NCBI Taxonomy and E-utilities documentation
Brunton "Bayesian optimization" lecture (search in his channel; verify)
In: LABLOOP-W11 Notebook
8/12
Watch
15 min?
W12
Saturday
Sandbox
optional
Steve Brunton "Physics Informed Machine Learning" series
Saturday sandbox
· after arXiv endorsement page
Steve Brunton "Physics Informed Machine Learning" series (YouTube), first 2 videos
In: LABLOOP-W12 Notebook
6/13
Watch
15 min?
W13
Saturday
Sandbox
optional
Steve Brunton "Neural ODEs"
Saturday sandbox
Steve Brunton "Neural ODEs" (YouTube)
In: LABLOOP-W13 Notebook
9/13
Watch
15 min?
W13
Saturday
Sandbox
optional
Stanford CS197 (cs197.stanford.edu), lecture on "vertical paper structure"
Saturday sandbox
· after Karniadakis et al. (2021), "Physics-informed machine learning"
Stanford CS197 (cs197.stanford.edu), lecture on "vertical paper structure" (verify lecture title)
In: LABLOOP-W13 Notebook
6/10
Watch
15 min?
W15
Saturday
Sandbox
optional
StatQuest "Statistical Power, Clearly Explained"
Saturday sandbox
· after ASAPbio preprint FAQ
StatQuest "Statistical Power, Clearly Explained" — reviewers may ask whether 50 gold papers is enough
In: LABLOOP-W15 Notebook
6/14
Watch
8 min
W16
Saturday
Sandbox
optional
DeepMind, "AlphaFold: The making of a scientific breakthrough"
Saturday sandbox
· after Rives et al. (2021), "Biological structure and function emerge from scaling unsupervised learnin…
DeepMind, "AlphaFold: The making of a scientific breakthrough" (YouTube, 8 min) — the emotional context of protein AI
In: LABLOOP-W16 Notebook
7/14
Watch
15 min?
W16
Saturday
Sandbox
optional
Nobel Prize in Chemistry 2024 lectures
Saturday sandbox
· after DeepMind, "AlphaFold: The making of a scientific breakthrough"
Nobel Prize in Chemistry 2024 lectures (Baker, Hassabis, Jumper) — nobelprize.org
In: LABLOOP-W16 Notebook
8/14
Watch
15 min?
W16
Saturday
Sandbox
optional
Anastasios Angelopoulos' conformal prediction tutorial videos
Saturday sandbox
· after Nobel Prize in Chemistry 2024 lectures
Anastasios Angelopoulos' conformal prediction tutorial videos (YouTube; verify)
In: LABLOOP-W16 Notebook
9/14
Watch
15 min?
W16
Saturday
Sandbox
optional
Valence Labs (YouTube), search "ESM" or "protein language models"
Saturday sandbox
· after Anastasios Angelopoulos' conformal prediction tutorial videos
Valence Labs (YouTube), search "ESM" or "protein language models" in the M2D2 reading group
In: LABLOOP-W16 Notebook
4/13
Watch
15 min?
W17
Saturday
Sandbox
optional
Yang, Wu & Arnold (2019), "Machine-learning-guided directed evolution for protein engineering"
Saturday sandbox
Yang, Wu & Arnold (2019), "Machine-learning-guided directed evolution for protein engineering", Nature Methods 16:687-694. The classic review; read it before week 21
In: LABLOOP-W17 Notebook
5/13
Watch
15 min?
W17
Saturday
Sandbox
optional
Frances Arnold, Nobel Lecture 2018 "Innovation by Evolution: Bringing New Chemistry to Life"
Saturday sandbox
· after Yang, Wu & Arnold (2019), "Machine-learning-guided directed evolution for protein engineering"
Frances Arnold, Nobel Lecture 2018 "Innovation by Evolution: Bringing New Chemistry to Life" (nobelprize.org)
In: LABLOOP-W17 Notebook
6/10
Watch
15 min?
W18
Saturday
Sandbox
optional
Stanford CS197, lecture on "writing the paper"
Saturday sandbox
· after Rothschild & Mancinelli (2001), "Life in extreme environments"
Stanford CS197, lecture on "writing the paper" (verify title)
In: LABLOOP-W18 Notebook
4/10
Watch
15 min?
W19
Saturday
Sandbox
optional
MIT 6.874 single-cell lecture
Saturday sandbox
· after Single-cell best practices
MIT 6.874 single-cell lecture (Kellis, YouTube)
In: LABLOOP-W19 Notebook
5/10
Watch
15 min?
W20
Saturday
Sandbox
optional
Stanford CS197 lecture on research talks and posters
Saturday sandbox
· after Richard Hamming, You and Your Research
Stanford CS197 lecture on research talks and posters (verify title)
In: LABLOOP-W20 Notebook
5/13
Watch
15 min?
W21
Saturday
Sandbox
optional
Valence Labs
Saturday sandbox
· after Yang, Wu & Arnold
Valence Labs (YouTube) reading-group talks on protein language models
In: LABLOOP-W21 Notebook
6/13
Watch
15 min?
W21
Saturday
Sandbox
optional
Frances Arnold on iBiology
Saturday sandbox
· after Valence Labs
Frances Arnold on iBiology (directed evolution talks; verify)
In: LABLOOP-W21 Notebook
2/10
Watch
15 min?
W22
Saturday
Sandbox
optional
Cunningham, Causal Inference: The Mixtape
Saturday sandbox
Cunningham, Causal Inference: The Mixtape — mixtape.scunning.com, ch. 3 (directed acyclic graphs)
In: LABLOOP-W22 Notebook
4/10
Watch
15 min?
W22
Saturday
Sandbox
optional
Coursera A Crash Course in Causality
Saturday sandbox
· after Huntington-Klein, The Effect
Coursera A Crash Course in Causality (Penn), week 1
In: LABLOOP-W22 Notebook
2/9
Watch
15 min?
W23
Saturday
Sandbox
optional
UniProt REST API documentation
Saturday sandbox
UniProt REST API documentation (rest.uniprot.org) and the BRENDA enzyme database (brenda-enzymes.org) for reported temperature optima
In: LABLOOP-W23 Notebook
3/9
Watch
15 min?
W23
Saturday
Sandbox
optional
iBiology talks on extremophiles and enzymes
Saturday sandbox
· after UniProt REST API documentation
iBiology talks on extremophiles and enzymes (search; verify)
In: LABLOOP-W23 Notebook
4/9
Watch
15 min?
W23
Saturday
Sandbox
optional
Crash Course Biology #35 "Old & Odd"
Saturday sandbox
· after iBiology talks on extremophiles and enzymes
Crash Course Biology #35 "Old & Odd" (carry over)
In: LABLOOP-W23 Notebook
5/12
Watch
15 min?
W25
Saturday
Sandbox
optional
StatQuest on ANOVA and "Design matrices"
Saturday sandbox
· after Bambi documentation
StatQuest on ANOVA and "Design matrices" (search in channel)
In: LABLOOP-W25 Notebook
5/11
Watch
15 min?
W26
Saturday
Sandbox
optional
Midani, Collins & Britton (2021), "AMiGA: software for automated analysis of microbial growth as…
Saturday sandbox
· after Sprouffske & Wagner
Midani, Collins & Britton (2021), "AMiGA: software for automated analysis of microbial growth assays", mSystems 6:e00508-21 — an open-source Python tool that fits growth curves without assuming their shape (pip install amiga)
In: LABLOOP-W26 Notebook
7/11
Watch
15 min?
W26
Saturday
Sandbox
optional
Khan Academy / LabXchange on spectrophotometry and optical density
Saturday sandbox
· after NCATS Assay Guidance Manual
In: LABLOOP-W26 Notebook
3/10
Watch
15 min?
W27
Saturday
Sandbox
optional
David Maister, Charles Green & Robert Galford, The Trusted Advisor
Saturday sandbox
David Maister, Charles Green & Robert Galford, The Trusted Advisor (book, paid) — the trust equation
In: LABLOOP-W27 Notebook
5/10
Watch
15 min?
W27
Saturday
Sandbox
optional
Stanford eCorner (ecorner.stanford.edu) — search talks on "customer discovery"
Saturday sandbox
· after Alan Weiss, Value-Based Fees
Stanford eCorner (ecorner.stanford.edu) — search talks on "customer discovery" and "B2B sales for technical founders"
In: LABLOOP-W27 Notebook
1/6
Watch
15 min?
W28
Saturday
Sandbox
optional
Getting to Yes
Saturday sandbox
Getting to Yes (Fisher, Ury & Patton; book, paid) — principled negotiation, if price is contested
In: LABLOOP-W28 Notebook
2/6
Watch
15 min?
W28
Saturday
Sandbox
optional
Stanford eCorner talks on first customers
Saturday sandbox
· after Getting to Yes
Stanford eCorner talks on first customers (search)
In: LABLOOP-W28 Notebook
4/8
Watch
15 min?
W31
Saturday
Sandbox
optional
Stanford CS197 lecture on co-authoring and feedback
Saturday sandbox
· after Target journal author guidelines chosen with the partner
Stanford CS197 lecture on co-authoring and feedback (verify)
In: LABLOOP-W31 Notebook
2/7
Watch
15 min?
W37
Saturday
Sandbox
optional
The Trusted Advisor
Saturday sandbox
· after Chip Huyen, Designing Machine Learning Systems
The Trusted Advisor (carry over) for running a pilot relationship
In: LABLOOP-W37 Notebook
1/6
Watch
15 min?
W38
Saturday
Sandbox
optional
Nancy Duarte, "The secret structure of great talks"
Saturday sandbox
Nancy Duarte, "The secret structure of great talks" (TEDx, YouTube)
In: LABLOOP-W38 Notebook
1/6
Watch
15 min?
W40
Saturday
Sandbox
optional
Uri Alon's talk and essay on "the cloud" in research
Saturday sandbox
Uri Alon's talk and essay on "the cloud" in research (iBiology; verify)
In: LABLOOP-W40 Notebook