WEEK 31 · Mon 19 Apr → Sun 25 Apr 2027

Paper 3 coauthor draft

600 minutes max9 deliverables enzymelens
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UNDERSTAND · PRACTICE · KEEP EVIDENCE

Your full learning notebook

Read the week in plain language, refresh the foundations, follow each challenge step by step, and check what evidence to keep. Includes worked examples, answer keys and prompts for visual study resources.

Use this within your existing weekly blocks. Your learning completion and research evidence remain in your current tracker and week files.

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START HERE · 2 MINUTES

What am I doing right now?

If you only complete one thing:
✓

STATUS

Tracker & deliverables

DeliverableAcceptanceState
paper-3-methods-draft.md
Build create +
Write introduction and methods from the versioned protein-study protocol, splits, embeddings and any partner assay protocol. Acceptance: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.
paper-3-results-draft.md
Build create +
Write results/limitations from frozen tables, include negative results, and run a skeptical methods review. Acceptance: No computational candidate is described as wet-lab validated without evidence.
coauthor-review-package.md
Build create +
Prepare the complete manuscript, contribution statement and question list for every proposed author and the lab reviewer. Acceptance: Review requests and returned author decisions are separately tracked.
study-notes.md
Learning create +
Selected exact free resources; bounded lesson/exercise; separate solution; quiz and grading rubric; Peter's answers and gaps when executed
founder-paper.md
Founder papers create +
Verified source and P11 digest; authentic question and connection sentence; access limitations
branding-pack.md
Branding create +
Wednesday note, Sunday build log, X adaptation, figure/caption/alt text and the week's special asset; each claim linked to real proof
opportunity-actions.md
Opportunities create +
Qualified target/role, source/date, ladder stage, next action, message/interview/proposal draft and actual status
evidence.md
Evidence & review open & edit ↗
Actual paths/URLs, versions, checks/metrics, preparation versus execution state and external receipts when applicable
review.md
Evidence & review open & edit ↗
Checklist, learning assessment, gate status, shortfalls, next actions and carryover
Notes on artifact states

These filenames are outputs to prepare during this week's execution; this scaffold does not claim they already exist. Drafts and measured results have different states. Technical code/data stay in the canonical project repository and are referenced from these coordinating files.

During preparation, future measured tables get column definitions, input requirements and run instructions with PENDING status. During execution, replace pending values only with measured outputs. Do not create realistic-looking fake evidence.

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600 MINUTES MAXIMUM

Seven-day plan

Monday90 min

Target. Write introduction and methods from the versioned protein-study protocol, splits, embeddings and any partner assay protocol. Stop when: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.

No material for Monday — this is a pure build day. Need something to study instead? →

Tuesday90 min· 2 cards, 75 min

Target. Review the research-writing checklist and one closely related protein study's methods/limitations. Produce: One concise applied note, a worked decision/example and unresolved questions.

Do these in this order — the plan's own sequence:

  1. Read Gopen & Swan 30 min find ↗
  2. Read Coursera Writing in the Sciences (Stanford), module on "Discussion" 45 min · after Gopen & Swan find ↗
Wednesday90 min

Target. Write results/limitations from frozen tables, include negative results, and run a skeptical methods review. Stop when: No computational candidate is described as wet-lab validated without evidence. Reserve the last 10 minutes for the optional Wednesday note.

No material for Wednesday — this is a pure build day. Need something to study instead? →

Thursday90 min

Target. Work through model/human review issues and co-author questions; retain 30 minutes for a directly relevant paper. Apply the Half 2 one-formal-study-block rule.

No material for Thursday — this is a pure build day. Need something to study instead? →

Friday90 min

Target. Prepare the complete manuscript, contribution statement and question list for every proposed author and the lab reviewer. Stop when: Review requests and returned author decisions are separately tracked.

No material for Friday — this is a pure build day. Need something to study instead? →

Saturday90 min

Target. Resolve the earliest critical spillover or dependency. Prepare any long-form publication draft from existing figures here if needed. Sandbox only after commitments are met.

Optional, only if the day went well:

  1. Read Target journal author guidelines chosen with the partner Saturday sandbox · 30 min? find ↗
  2. Watch Stanford CS197 lecture on co-authoring and feedback Saturday sandbox · 15 min? · after Target journal author guidelines chosen with the partner find ↗
  3. Read Whitesides 2004 Saturday sandbox · 30 min? · after Stanford CS197 lecture on co-authoring and feedback find ↗
Sunday60 min

Target. 20 min build-log draft/publication when authorized; 5 min evidence/checklist; 20 min source-grounded gap review; 15 min next week's six physical actions.

No material for Sunday — this is a pure build day. Need something to study instead? →

Any time this week3 cards, 90 min · the plan names no day for these

Spare pockets, repo exercises and anything the plan lists without a day. Take them in this order when a day finishes early.

  1. Run quarto-dev/quarto-cli 30 min open ↗
  2. Run enzymelens (yours) 30 min find ↗
  3. Run Future-House/paper-qa 30 min open ↗
Block ritual: read your next action → start the 90-min timer → open one file. Close: write tomorrow's action and one log line.
Feels pointless? Does today's Done when need it? No → skip it and log it. Yes → let AI do the boring part, you review. Still stuck → the smallest version in 25 minutes. Pulled into a rabbit hole? Write it in Parked thoughts and save it for Saturday.

The model must turn these into exact physical actions using the observed files and available inputs. Each 90-minute block includes start/stop rituals. All calls, posts, debugging, reading and exercises consume this same capacity.

Half 2: Tuesday is the formal study block unless this is a selling/submission/decision week. Thursday supports applied review, partner work or the market task; do not add another full course.

◎

WHAT TO WATCH, READ AND RUN

Materials for this week

Writing with a co-author is like cooking in someone else's kitchen: you bring your recipe, they know where everything is, and the dish is better when you respect their habits. Your partner knows what biologists expect in a validation section, which claims will embarrass them in front of peers, and which journals their community reads. You know how to make every number reproducible. This week you use the same writing…

0 of 8 finished · give me one to start now → · open in the deck →

In the plan's running order: each card says which block it belongs to and what has to come before it. The seven-day plan lists the same cards under the day that owns them.

Tuesday 2 · 75 min total

1/8 Read 30 min W31 Tuesday Biology

Gopen & Swan

Gopen & Swan (1990) re-read (30 min)

Find it ↗ search

In: LABLOOP-W31 Notebook

2/8 Read 45 min W31 Tuesday Biology

Coursera Writing in the Sciences (Stanford), module on "Discussion"

Tuesday · after Gopen & Swan

Coursera Writing in the Sciences (Stanford), module on "Discussion" and "Abstract" (45 min)

Find it ↗ search

In: LABLOOP-W31 Notebook

Saturday · sandbox, optional 3 · 75 min total

3/8 Read 30 min? W31 Saturday Sandbox optional

Target journal author guidelines chosen with the partner

Saturday sandbox

Target journal author guidelines chosen with the partner (e.g., a protein engineering or applied microbiology journal; verify fit and open-access policy)

Find it ↗ search

In: LABLOOP-W31 Notebook

4/8 Watch 15 min? W31 Saturday Sandbox optional

Stanford CS197 lecture on co-authoring and feedback

Saturday sandbox · after Target journal author guidelines chosen with the partner

Stanford CS197 lecture on co-authoring and feedback (verify)

Find it ↗ search

In: LABLOOP-W31 Notebook

5/8 Read 30 min? W31 Saturday Sandbox optional

Whitesides 2004

Saturday sandbox · after Stanford CS197 lecture on co-authoring and feedback

Whitesides 2004 (carry over)

Find it ↗ search

In: LABLOOP-W31 Notebook

Any block this week — the plan names no day 3 · 90 min total

6/8 Run 30 min W31 Build

quarto-dev/quarto-cli

Paper 3 manuscript; export to .docx for a co-author who uses Word track changes

Open ↗

In: LABLOOP-W31 Notebook

7/8 Run 30 min W31 Build

enzymelens (yours)

make paper from a clean clone; tag paper-3-draft-1

Find it ↗ search

In: LABLOOP-W31 Notebook

8/8 Run 30 min W31 Build

Future-House/paper-qa

Check the Discussion's claims about prior work against the PDFs you cite (verify manually)

Open ↗

In: LABLOOP-W31 Notebook

01

READ FIRST

Outcome and relevance

This week delivers the three concrete artifacts below and the supporting learning/branding/opportunity pack. The scientific or commercial outcome follows the preserved source brief, while the acceptance checks make its evidence testable. The career objective is to turn this work into something a scientist, hiring manager or buyer can inspect.

  • Scientific/build priority: Write introduction and methods from the versioned protein-study protocol, splits, embeddings and any partner assay protocol.
  • Public/profile priority: Prepare a writing-process note and an evidence-backed protein-ML portfolio bullet.
  • Career/relationship/commercial priority: Update qualified hiring contacts on concrete work; prepare co-author review requests and close audit acceptance issues.
02

READ FIRST

Deeper walkthrough (v6)

Read v6 · Week 31 · Write Paper 3 before Monday. It expands this week's one-row v5 brief into daily build steps and adds the Welcome analogy, Learn it (▶ core and + deeper sources), Run it (repos with a 20-40 minute exercise), the NotebookLM kit and the mentor check below. Standing v6 rules: resource rules, NotebookLM protocol, chapter anatomy. v6 adds depth only; it does not change a goal, gate, output or the 600-minute cap, so this specification still governs execution.

Act VI · Threads: EL, R · Next gate: 32

Where this week sits. - ← From: weeks 21-30 (model, candidates, validation); weeks 14-18 writing craft. - → Feeds: week 32 (preprint), week 36 (journal choice), week 38 (talk), Part 9 headline ("co-author with [lab]"). - ⟳ Returns in: the relationship: co-authors refer clients, students and future papers.

Goals. - 🎯 This week: Paper 3 draft with co-author comments incorporated; P10 run; co-author's lab has read it. - 🏁 Next milestone: Gate 32. - 🌟 Final: L4 co-authored.

The plan (from v5 Part 7, expanded; gate and output unchanged).

v5 row: 31 | Write Paper 3 | Research craft refresher | Draft with co-author; Prompt P10; co-author's lab reads it | Draft to co-author - Goal: a draft both authors are proud of. - Tue (study): research craft refresher (Gopen & Swan re-read; Writing in the Sciences module on discussion sections). - Build: Mon: skeleton (P9) with the partner's section preferences; Methods (computational) by you, Methods (wet lab) by the partner. Wed: Results and Discussion draft; P10 twice. Fri: draft to co-author; CRediT statement; data and code availability agreed. - Sun: no public post about unpublished results. - Only one thing: draft sent to the co-author.

Mentor check. "A biologist and I wrote the same paper, and both of us would defend every sentence."

03

OPEN WHEN NEEDED

Required inputs and dependency check

  • Week 22: inspect its actual evidence and review; source/code artifacts must exist before the dependent task begins.
  • Week 23: inspect its actual evidence and review; source/code artifacts must exist before the dependent task begins.
  • Week 24: inspect its actual evidence and review; source/code artifacts must exist before the dependent task begins.
  • Week 30: inspect its actual evidence and review; source/code artifacts must exist before the dependent task begins.
  • Read commitment, evidence, review and the current root TODAY/PROGRESS/QUESTIONS files.
  • Read this week's chapter, v6 · Week 31 · Write Paper 3, then the standing sections: Part 0 · how to use the document, Part 3 · the scientific thesis, Part 4 · curriculum, Part 8 · the prompt pack and Part 9 · branding and endorsement. The same sections exist in the v5 master, which remains the governing sequence; v6 reproduces them and adds depth. Retained commercial/instrument details come from v4.
  • Inspect the actual canonical repository state, available data, existing figures and required human/external inputs. Never assume a previous week succeeded from its folder name.
  • Verify current resource links, versions, dataset rights and any live company/venue information before relying on them. Use source catalog; explicitly record inaccessible resources.
04

READ FIRST

Learning specification

Biology/domain unit

Material: Review the research-writing checklist and one closely related protein study's methods/limitations.

Produce: One concise applied note, a worked decision/example and unresolved questions.

Understanding check: The note directly supports this week's experiment, collaboration, delivery or career action.

During preparation, write one worked example connected to the week's actual task, one exercise with a separate answer key and five questions. Peter supplies answers; score explanation quality and flag misconceptions in QUESTIONS. Numeric/scientific conclusions require actual data or explicitly synthetic teaching values.

AI/scientific-method unit

Material: Work through model/human review issues and co-author questions; retain 30 minutes for a directly relevant paper.

Produce: One concise applied note, a worked decision/example and unresolved questions.

Understanding check: The note directly supports this week's experiment, collaboration, delivery or career action.

Use the prompt pack: P1 explanation ladder, P2 concept-to-project bridge and P3 quiz. Coding practice belongs within the allocated study/build block. Where the source asks for a favorable scientific result, substitute an honest measured comparison as explained below.

Founder/scientist paper

Select one verified founder/scientific-lead paper relevant to this week's domain. Use P11; save the question, method, numerical result with context, data workflow, three author questions and one connection sentence in founder-paper.md. Keep abstract-only access limitations explicit. On source weeks with no study, prioritize the commercial/submission task and log any skipped digest.

05

OPEN WHEN NEEDED

Branding and opportunity execution brief

Branding: Prepare a writing-process note and an evidence-backed protein-ML portfolio bullet.

Opportunity action: Update qualified hiring contacts on concrete work; prepare co-author review requests and close audit acceptance issues.

Use career asset contracts. Publish at most the agreed cadence; one figure and one supported number or admitted failure can support multiple drafts. In long-form weeks, prepare a 1,500–2,500-word article from existing evidence within the build/buffer allocation. In release/demo weeks, prepare a 60-second script: problem, input, command/action, result, limitation and proof link.

Verify individuals, jobs and affiliations at execution time. The GridX list and v4 company map are research seeds, not current facts. Do not reveal named company weaknesses or employer/client confidential information. Keep drafted/sent/replied/booked/held statuses separate. The planning request alone does not authorize external messages or publication; honor explicit authorization in the execution session.

06

OPEN WHEN NEEDED

Quality risks and week-specific constraints

Without a contributing scientist, prepare a computational manuscript and disclose the missed co-authorship gate. Models cannot supply human authorship or approval.

Apply the root scientific evidence contract: provenance; meaningful independent splits; no future-data leakage; baseline comparison; actual denominators/uncertainty; failed cases; human review where required. State whether data are simulated, public experimental, synthetic or partner-provided.

Keep source gates intact, and log scope/time conflicts in review. Missing people, money, access or results must not be replaced with invented evidence. Reduce optional polish first. A specific essential external dependency stays pending while independent preparation continues.

07

READ FIRST

Completion and gate review

This is an enabling week. Its deliverables feed the next scheduled gate: 32. Complete the acceptance checklist below; do not promote reputation from a draft.

  • Monday artifact satisfies: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.
  • Wednesday artifact satisfies: No computational candidate is described as wet-lab validated without evidence.
  • Friday artifact satisfies: Review requests and returned author decisions are separately tracked.
  • Study pack is prepared; Peter's actual learning/quiz result is recorded separately.
  • Branding and opportunity drafts use supported claims and the correct external-action state.
  • Reproduction or document checks are recorded with file/version references.
  • This week's special gate, if any, has real evidence or remains explicitly pending.
  • Review, root progress/log and the next physical action are updated.
08

READ FIRST

Minimum viable week and recovery

Expanded minimum derived from the source goal: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.

Operational first step if stalled: open paper-3-methods-draft.md, write the required inputs and produce the smallest checkable example in ten minutes. If a more urgent missing gate dependency controls the week, use the source minimum above.

If the full week does not fit, use P14: retain one gate-critical deliverable and one directly supporting study exercise; record what is skipped versus moved. Do not mark the original full gate passed merely because the minimum was completed. After a missed week, reforecast from actual evidence and avoid a second unexamined lost week.

09

OPEN WHEN NEEDED

Handoff to the next model

In review, state exactly what exists, what was verified, what Peter can now explain, which external events remain pending, where the canonical code/data live, and the next file/function or draft paragraph to touch. Link each fact to evidence. Carry scientific assumptions, split definitions and rights constraints forward explicitly.

10

OPEN WHEN NEEDED

Ready-to-copy model prompt

Prepare Week 31 of this LABLOOP execution plan.
Read execution-plan/specs.md, execution-plan/DECISIONS.md,
execution-plan/GATES.md and
execution-plan/weeks/week-31-paper-3-coauthor-draft/specs.md, commitment.md, evidence.md and review.md.
Read prior prerequisite reviews and inspect actual repository/data state.
Use v5 as the governing sequence, the v6 Week 31 chapter
(LABLOOP-Master-Plan-v6.md) as the deeper walkthrough, and v4 only for
retained details.
Produce the full local preparation pack and the exact week-specific files named
in the artifact table. Give me a bounded lesson with exercises/answer key,
daily physical actions, technical runbook or draft, branding drafts and
career/commercial actions. Keep the total to 600 minutes.
Separate prepared artifacts from measured results and my learning completion.
Verify sources and do not invent metrics, citations, papers, people or outcomes.
Do not execute external communications, publication or spending unless the
current session already authorizes the specific action.
Finish by updating evidence/review and TODAY with the next physical action.
11

OPEN WHEN NEEDED

Preserved original v5 weekly brief

v6 expands this row into a full brief, with the gate and output unchanged, inside v6 · Week 31 · Write Paper 3. The following is source planning text, not a claim of completion. Apply the explicit evidence corrections in this specification and DECISIONS.md.

Week Goal Study (Tue) Build (Mon/Wed/Fri) Output
31 Write Paper 3 Research craft refresher Draft with co-author; Prompt P10; co-author's lab reads it Draft to co-author
📄

WEEK FILES

Commitment · evidence · review

commitment.md open ↗

State: UNCONFIRMED. Owner: Peter Ciancaglini. Specification

Start date: not set. End date: not set. Available hours: confirm (planned ceiling 10). Primary outcome: paper 3 coauthor draft. Minimum that keeps the next gate alive: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.

Deliverables to commit

  • ☐ paper-3-methods-draft.md: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request.
  • ☐ paper-3-results-draft.md: No computational candidate is described as wet-lab validated without evidence.
  • ☐ coauthor-review-package.md: Review requests and returned author decisions are separately tracked.
  • ☐ Bounded learning exercise and personal teach-back.
  • ☐ Evidence-backed branding and opportunity pack.
  • ☐ Sunday review and next physical action.

Proposed calendar

Day Minutes Physical action / outcome Actual slot Done
Mon 90 Write introduction and methods from the versioned protein-study protocol, splits, embeddings and any partner assay protocol. Not set ☐
Tue 90 One concise applied note, a worked decision/example and unresolved questions. Not set ☐
Wed 90 Write results/limitations from frozen tables, include negative results, and run a skeptical methods review. Last ten minutes: optional note. Not set ☐
Thu 90 One concise applied note, a worked decision/example and unresolved questions. Include relevant founder-paper work within this block. Not set ☐
Fri 90 Prepare the complete manuscript, contribution statement and question list for every proposed author and the lab reviewer. Not set ☐
Sat 90 Resolve critical spillover; long-form draft if due; sandbox only if done. Not set ☐
Sun 60 Build log, evidence, gap review, next actions. Not set ☐

Dependency and capacity check

  • Missing essential inputs: not yet inspected.
  • Human/external dependency, owner and expected date: not yet inspected.
  • Week-specific constraint: Without a contributing scientist, prepare a computational manuscript and disclose the missed co-authorship gate. Models cannot supply human authorship or approval.
  • Existing session authorization for external actions or spending: not assessed; local planning only at scaffold creation.
  • Scope to cut first: optional polish/additional examples; preserve scientific validity.
  • If the forecast exceeds available time: record a concrete reduced scope or revised delivery proposal before committing.

Peter's commitment / adjustments: pending. Reviewing model and date: pending.

evidence.md open ↗

Execution state: NOT_STARTED. Specification This file is a blank register with planned artifact names; none of the rows prove completion.

Item Path / URL / version State Verification / actual result Verified by / date
paper-3-methods-draft.md Not created NOT_STARTED Pending: The exact target quantity and experimental/computational scope are explicit. —
paper-3-results-draft.md Not created NOT_STARTED Pending: No computational candidate is described as wet-lab validated without evidence. —
coauthor-review-package.md Not created NOT_STARTED Pending: Review requests and returned author decisions are separately tracked. —
Learning exercise / Peter's quiz Not created NOT_STARTED Peter's actual answers required —
Founder paper digest Not created NOT_STARTED Source/content and access checked —
Branding pack Not created NOT_STARTED Claims audited; drafted/public status distinct —
Opportunity actions Not created NOT_STARTED Drafted/sent/replied/booked/held distinct —

Reproduction and scientific measurements

Question / metric Dataset, N and unit Split / seed / config Command or verification method Output path and measured value Uncertainty / limitation

External events, when authorized and actually performed

Date Action / counterpart Receipt or private reference State Next action / date

Actual learning and decisions

Peter's teach-back / quiz score: not assessed. Scientific assumptions and deviations: none recorded yet. Budget allocated / spent: not assessed / no spend recorded. Missing evidence and responsible owner: pending inspection.

Do not put API keys, source full texts with restricted rights, client data or invoice personal details in a public version of this register. Keep private evidence references private.

review.md open ↗

Review status: NOT_REVIEWED. Specification · Evidence

What was actually completed?

  • ☐ Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request. Evidence: pending.
  • ☐ No computational candidate is described as wet-lab validated without evidence. Evidence: pending.
  • ☐ Review requests and returned author decisions are separately tracked. Evidence: pending.
  • ☐ Learning assessed from Peter's actual answers. Evidence: pending.
  • ☐ Branding/opportunity states recorded correctly. Evidence: pending.

Learning and outcome

What Peter can explain or reproduce now: not assessed. Quiz / teach-back gaps: not assessed. Measured result and limitations: pending. Best evidence link for a scientist/recruiter/buyer: pending. What failed or changed, and why: pending.

Gate and capacity

Gate requirement: No standalone gate; check this week's acceptance criteria and next gate dependencies. Gate status: NOT_STARTED. Original target week: See next gate in specs. Actual completion date / forecast: not set. Missing external evidence: pending inspection. Blocks completed / 7: not recorded. Days with commits / 7: not recorded. Sunday build log / optional Wednesday note: not recorded. Founder conversations cumulative: not recorded. Earned evidence level and proof: not assessed. Consecutive lost weeks: not assessed.

Week-specific risk to revisit: Without a contributing scientist, prepare a computational manuscript and disclose the missed co-authorship gate. Models cannot supply human authorship or approval.

Decision and next-model handoff

Continue / recover / blocked: not decided. Retain as the minimum: Produce Paper 3 methods/results draft from actual evidence and prepare the co-author review request. Skipped permanently with reason: none recorded. Carryover with owner, dependency and target week: none recorded. Canonical repository paths and versions: pending. Data permissions, split definitions or assumptions to preserve: pending. External action authorization that still applies: not assessed. Next physical action, exact file/function/paragraph: pending. Updates to root PROGRESS / LOG / TODAY completed: ☐

Next week

✎

YOUR SPACE

Notes, links & media

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    ⏱ Focus Focus25:00 0 min today