There is an old trick in sales: compare your product with a weak competitor and you always win. Science has the same trick, and reviewers hunt for it. The honest move is to compare against the strongest published baseline, on the exact same splits, and to split proteins by family so the model cannot cheat by recognising a close cousin it saw in training (like a student who memorised last year's exam because this yea…
If you only do one thing this week: the family-split table
Partner-recommended reading (ask for it); if none yet, Rothschild & Mancinelli (2001) "Life in e…
Partner-recommended reading (ask for it); if none yet, Rothschild & Mancinelli (2001) "Life in extreme environments" (carry over) and the UniProt "Help" pages on EC numbers and taxonomy filters (75 min)