execution-plan/weeks/week-23-extremophile-candidate-ranking/commitment.md · UPDATED 2026-09-16

Week 23 commitment

3 parts423 words 6 checkboxes — tick them, they save to the file

State: UNCONFIRMED. Owner: Peter Ciancaglini. Specification

Start date: not set. End date: not set. Available hours: confirm (planned ceiling 10). Primary outcome: extremophile candidate ranking. Minimum that keeps the next gate alive: Produce five traceable candidate entries with uncertainty, sequence provenance and partner-relevance rationale.

Deliverables to commit

candidate-source-manifest.csv: Produce five traceable candidate entries with uncertainty, sequence provenance and partner-relevance rationale.
ranked-candidates.csv: Every candidate has evidence, confidence limits and limitations; scores are not laboratory results.
partner-candidate-dossier.md: Partner can assess feasibility and choose candidates without a hidden model assumption.
Bounded learning exercise and personal teach-back.
Evidence-backed branding and opportunity pack.
Sunday review and next physical action.

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Proposed calendar

Day	Minutes	Physical action / outcome	Actual slot	Done
Mon	90	Define the partner enzyme family, organism scope and assay-compatible inclusion rules; acquire versioned UniProt records.	Not set	[ ]
Tue	90	One concise applied note, a worked decision/example and unresolved questions.	Not set	[ ]
Wed	90	Predict/rank candidates with uncertainty, similarity-to-training and out-of-domain flags; include simple baseline rankings. Last ten minutes: optional note.	Not set	[ ]
Thu	90	One concise applied note, a worked decision/example and unresolved questions. Include relevant founder-paper work within this block.	Not set	[ ]
Fri	90	Prepare a candidate dossier and collaboration note covering contribution, data access, publication intent and dependencies.	Not set	[ ]
Sat	90	Resolve critical spillover; long-form draft if due; sandbox only if done.	Not set	[ ]
Sun	60	Build log, evidence, gap review, next actions.	Not set	[ ]

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Dependency and capacity check

Missing essential inputs: not yet inspected.
Human/external dependency, owner and expected date: not yet inspected.
Week-specific constraint: If partner material is confidential, keep public-data analysis separate. No invented extremophile labels or claims of discovering a superior enzyme.
Existing session authorization for external actions or spending: not assessed; local planning only at scaffold creation.
Scope to cut first: optional polish/additional examples; preserve scientific validity.
If the forecast exceeds available time: record a concrete reduced scope or revised delivery proposal before committing.

Peter's commitment / adjustments: pending. Reviewing model and date: pending.

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