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WEEK 17 · PAPER 2 EXPERIMENTS, COMPLETE

Do one thing.
Then you are ahead.

A clinical trial is not "we gave the drug to some people and they felt better". It is arms, doses, randomisation, repeats, and a pre-declared outcome. This week Paper 2 becomes a proper trial. Three arms (mechanistic, pure ML, hybrid), four "doses" of data (5, 10, 20, 50 batches), five seeds each so luck cannot fake a result, conformal intervals so every number carries its honest uncertainty, and a stress test on fa…

If you only do one thing this week: the learning curves with seeds
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THE NEXT BLOCK

How long have you got?

10 min 25 min 50 min 90 min 13 of 13 cards still open in week 17 · 11 finished overall
9/14 Watch 15 min? W16 Saturday Sandbox optional

Valence Labs (YouTube), search "ESM" or "protein language models"

Saturday sandbox · after Anastasios Angelopoulos' conformal prediction tutorial videos

Valence Labs (YouTube), search "ESM" or "protein language models" in the M2D2 reading group

Find it ↗ search

In: LABLOOP-W16 Notebook

By Sunday you should be able to say: “I can show the learning curve and say, with an interval, below how many batches the hybrid model is the better bet.”

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MOMENTUM

What you have actually done

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