execution-plan/weeks/week-22-protein-validation-and-baselines/commitment.md · UPDATED 2026-09-16

Week 22 commitment

3 parts433 words 6 checkboxes — tick them, they save to the file

State: UNCONFIRMED. Owner: Peter Ciancaglini. Specification

Start date: not set. End date: not set. Available hours: confirm (planned ceiling 10). Primary outcome: protein validation and baselines. Minimum that keeps the next gate alive: Produce protein-split-audit.md and one held-out baseline score with no family leakage; an unfavorable score is still evidence.

Deliverables to commit

protein-split-audit.md: Produce protein-split-audit.md and one held-out baseline score with no family leakage; an unfavorable score is still evidence.
protein-comparison.csv: MAE/RMSE/rank metrics, N and group-aware uncertainty accompany results.
protein-uncertainty.md: A held-out table exists whether or not the stronger model wins.
Bounded learning exercise and personal teach-back.
Evidence-backed branding and opportunity pack.
Sunday review and next physical action.

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Proposed calendar

Day	Minutes	Physical action / outcome	Actual slot	Done
Mon	90	Define family/sequence-cluster grouped splits and keep homologous proteins out of independent partitions; document thresholds and counts.	Not set	[ ]
Tue	90	One concise applied note, a worked decision/example and unresolved questions.	Not set	[ ]
Wed	90	Evaluate heads against simple sequence/composition and published baselines where targets and splits are comparable. Last ten minutes: optional note.	Not set	[ ]
Thu	90	One concise applied note, a worked decision/example and unresolved questions. Include relevant founder-paper work within this block.	Not set	[ ]
Fri	90	Add calibrated intervals where assumptions are appropriate and record confounding and out-of-distribution failure cases.	Not set	[ ]
Sat	90	Resolve critical spillover; long-form draft if due; sandbox only if done.	Not set	[ ]
Sun	60	Build log, evidence, gap review, next actions.	Not set	[ ]

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Dependency and capacity check

Missing essential inputs: not yet inspected.
Human/external dependency, owner and expected date: not yet inspected.
Week-specific constraint: Published FLIP and custom family-split scores cannot be ranked as apples-to-apples without reproducing the same task. No guaranteed conformal coverage under distribution shift.
Existing session authorization for external actions or spending: not assessed; local planning only at scaffold creation.
Scope to cut first: optional polish/additional examples; preserve scientific validity.
If the forecast exceeds available time: record a concrete reduced scope or revised delivery proposal before committing.

Peter's commitment / adjustments: pending. Reviewing model and date: pending.

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